Article
Evolutionary dynamics of GII.4 noroviruses over a 34-year period.
Journal of virology - 1 Nov 2009
Bok Karin, Abente Eugenio J, Realpe-Quintero Mauricio, Mitra Tanaji, Sosnovtsev Stanislav V, Kapikian Albert Z, Green Kim Y
Abstract excerpt
Noroviruses are a major cause of epidemic gastroenteritis in children and adults, and GII.4 has been the predominant genotype since its first documented occurrence in 1987. This study examined the evolutionary dynamics of GII.4 noroviruses over more than three decades to investigate possible mechanisms by which these viruses have emerged to become predominant. Stool samples (n = 5,424) from children hospitalized...
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