Article
Rapid evolution of pandemic noroviruses of the GII.4 lineage.
PLoS pathogens - 26 Mar 2010
Bull Rowena A, Eden John-Sebastian, Rawlinson William D, White Peter A
Abstract excerpt
Over the last fifteen years there have been five pandemics of norovirus (NoV) associated gastroenteritis, and the period of stasis between each pandemic has been progressively shortening. NoV is classified into five genogroups, which can be further classified into 25 or more different human NoV genotypes; however, only one, genogroup II genotype 4 (GII.4), is associated with pandemics. Hence, GII.4 viruses have...
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