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Article

Minimal Antigenic Evolution after a Decade of Norovirus GII.4 Sydney_2012 Circulation in Humans.

Journal of virology - 28 Feb 2023

Parra Gabriel I, Tohma Kentaro, Ford-Siltz Lauren A, Eguino Patricia, Kendra Joseph A, Pilewski Kelsey A, Gao Yamei

Abstract excerpt

Norovirus is a major human pathogen that can cause severe gastroenteritis in vulnerable populations. The extensive viral diversity presented by human noroviruses constitutes a major roadblock for the development of effective vaccines. In addition to the large number of genotypes, antigenically distinct variants of GII.4 noroviruses have chronologically emerged over the last 3 decades. The last variant to emerge,...

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Antibodies, Monoclonal
Antigens, Viral
Caliciviridae Infections
Capsid Proteins
Epitopes

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Evolution, Molecular

Gastroenteritis

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Identifiers

PMID: 36688654
DOI: 10.1128/jvi.01716-22
PMCID: PMC9973034

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