Article
Minimal Antigenic Evolution after a Decade of Norovirus GII.4 Sydney_2012 Circulation in Humans.
Journal of virology - 28 Feb 2023
Parra Gabriel I, Tohma Kentaro, Ford-Siltz Lauren A, Eguino Patricia, Kendra Joseph A, Pilewski Kelsey A, Gao Yamei
Abstract excerpt
Norovirus is a major human pathogen that can cause severe gastroenteritis in vulnerable populations. The extensive viral diversity presented by human noroviruses constitutes a major roadblock for the development of effective vaccines. In addition to the large number of genotypes, antigenically distinct variants of GII.4 noroviruses have chronologically emerged over the last 3 decades. The last variant to emerge,...
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