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Article

The XS106 cell: a Langerhans' cell surrogate with a selective type 2 phenotype.

Cutaneous and ocular toxicology - 1 Dec 2014

Eaton Laura H, Mellody Kieran T, Kimber Ian, Dearman Rebecca J

Abstract excerpt

Epidermal Langerhans' cells (LC) play important roles in initiating and regulating cutaneous immune responses. However, LC comprise less than 3% of all epidermal cells and consequently are difficult to study ex vivo. In the current investigations, we have examined the utility of the XS106 cell line, a dendritic cell (DC) line derived from mouse epidermis, as a surrogate for LC. Membrane marker expression, type 1-...

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Identifiers

PMID: 24641122
DOI: 10.3109/15569527.2013.873046

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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