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Article

Reduced B lymphoid kinase (Blk) expression enhances proinflammatory cytokine production and induces nephrosis in C57BL/6-lpr/lpr mice.

PloS one - 1 Jan 2014

Samuelson Elizabeth M, Laird Renee M, Papillion Amber M, Tatum Arthur H, Princiotta Michael F, Hayes Sandra M

Abstract excerpt

BLK, which encodes B lymphoid kinase, was recently identified in genome wide association studies as a susceptibility gene for systemic lupus erythematosus (SLE), and risk alleles mapping to the BLK locus result in reduced gene expression. To determine whether BLK is indeed a bona fide susceptibil...

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Source

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Identifiers

PMID: 24637841
DOI: 10.1371/journal.pone.0092054
PMCID: PMC3956874

Genes

BLK

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24637841-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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Reduced B lymphoid kinase (Blk) expression enhances proinflammatory cytokine production and induces nephrosis in C57BL/6-lpr/lpr mice.PMID 24637841Read ↗

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