Article
Direct detection of the AR-E211 G > A gene polymorphism from blood and tissue samples without DNA isolation.
Pathology oncology research : POR - 1 Apr 2014
Reptova Silvie, Trtkova Katerina Smesny, Kolar Zdenek
Abstract excerpt
The pathogenesis of prostate cancer (CaP) involves alterations in a gene structure of the androgen receptor (AR). The single nucleotide polymorphism AR-E211 G > A localized in exon 1 of the AR gene (G1733A) was detected using direct polymerase chain reaction and restriction digestion (PCR-RFLP) m...
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