Article
Genetic variants determining body fat distribution and sex hormone-binding globulin among Chinese female young adults.
Journal of diabetes - 1 Nov 2014
Shi Juan, Li Lijuan, Hong Jie, Qi Lu, Cui Bin, Gu Weiqiong, Zhang Yifei, Miao Lin, Wang Rui, Wang Weiqing, Ning Guang
Abstract excerpt
BACKGROUND: Measures of body fat distribution (i.e. waist : hip ratio [WHR]) are major risk factors for diabetes, independent of overall adiposity. The genetic variants related to body fat distribution show sexual dimorphism and particularly affect females. Substantial literature supports a role for sex hormone-binding globulin (SHBG) in the maintenance of glucose homeostasis. The aim of the present study was to...
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