Article
High resolution structure and double electron-electron resonance of the zebrafish voltage-dependent anion channel 2 reveal an oligomeric population.
The Journal of biological chemistry - 2 May 2014
Schredelseker Johann, Paz Aviv, López Carlos J, Altenbach Christian, Leung Calvin S, Drexler Maria K, Chen Jau-Nian, Hubbell Wayne L, Abramson Jeff
Abstract excerpt
In recent years, there has been a vast increase in structural and functional understanding of VDAC1, but VDAC2 and -3 have been understudied despite having many unique phenotypes. One reason for the paucity of structural and biochemical characterization of the VDAC2 and -3 isoforms stems from the inability of obtaining purified, functional protein. Here we demonstrate the expression, isolation, and basic...
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