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Article

Role of cysteines in mammalian VDAC isoforms' function.

Biochimica et biophysica acta - 1 Aug 2016

De Pinto Vito, Reina Simona, Gupta Ankit, Messina Angela, Mahalakshmi Radhakrishnan

Abstract excerpt

In this mini-review, we analyze the influence of cysteines in the structure and activity of mitochondrial outer membrane mammalian VDAC isoforms. The three VDAC isoforms show conserved sequences, similar structures and the same gene organization. The meaning of three proteins encoded in different chromosomes must thus be searched for subtle differences at the amino acid level. Among others, cysteine content is...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 26947058
DOI: 10.1016/j.bbabio.2016.02.020
PMCID: PMC7115947

Genes

VDAC3
VDAC2
VDAC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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