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Article

The impact of MIR137 on dorsolateral prefrontal-hippocampal functional connectivity in healthy subjects.

Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology - 1 Aug 2014

Liu Bing, Zhang Xiaolong, Hou Bing, Li Jin, Qiu Chengxiang, Qin Wen, Yu Chunshui, Jiang Tianzi

Abstract excerpt

A recent mega-analysis combining genome-wide association study data revealed that a variant of microRNA 137 (MIR137) exhibits the most significant association with schizophrenia. Other biological evidence also consistently suggests that MIR137 may have a pivotal role in the pathogenesis of schizophrenia. However, the underlying neural mechanism remains unclear. As the disrupted dorsolateral prefrontal cortex...

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Identifiers

PMID: 24625753
DOI: 10.1038/npp.2014.63
PMCID: PMC4104332

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