Article
Association of FTO, LEPR and MTHFR gene polymorphisms with metabolic syndrome in schizophrenia patients receiving antipsychotics.
Pharmacogenomics - 1 Mar 2014
Roffeei Siti Norsyuhada, Mohamed Zahurin, Reynolds Gavin P, Said Mas Ayu, Hatim Ahmad, Mohamed Elsa Haniffah Mejia, Aida Syarinaz Ahmad, Zainal Nor Zuraida
Abstract excerpt
AIM: The occurrence of metabolic syndrome (MS) in schizophrenia patients receiving long-term antipsychotics (APs) contributes to their high mortality rate. We aimed to determine whether genetic polymorphisms of identified candidate genes are associated with MS in our study population. MATERIALS & METHODS: We recruited 206 schizophrenia patients receiving AP treatment for at least a year. Cross-sectional...
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