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Article

MTHFR and risk of metabolic syndrome in patients with schizophrenia.

Schizophrenia research - 1 Aug 2010

van Winkel Ruud, Rutten Bart P, Peerbooms Odette, Peuskens Joseph, van Os Jim, De Hert Marc

Abstract excerpt

OBJECTIVE: Meta-analyses have implicated polymorphisms in MTHFR, encoding a critical enzyme in folate and homocysteine metabolism, in both schizophrenia and CVD. METHOD: A possible association between the C677T and A1298C polymorphisms of the MTHFR gene on the one hand, and metabolic syndrome on the other, was examined in a naturalistic cohort of 518 patients with a schizophrenia spectrum disorder screened for...

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Identifiers

PMID: 20547447
DOI: 10.1016/j.schres.2010.05.030

Genes

MTHFR

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