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Article

The diamine oxidase gene is associated with hypersensitivity response to non-steroidal anti-inflammatory drugs.

PloS one - 1 Jan 2012

Agúndez José A G, Ayuso Pedro, Cornejo-García José A, Blanca Miguel, Torres María J, Doña Inmaculada, Salas María, Blanca-López Natalia, Canto Gabriela, Rondon Carmen, Campo Paloma, Laguna José J, Fernández Javier, Martínez Carmen, García-Martín Elena

Abstract excerpt

UNLABELLED: Non-steroidal anti-inflammatory drugs (NSAIDs) are the drugs most frequently involved in hypersensitivity drug reactions. Histamine is released in the allergic response to NSAIDs and is responsible for some of the clinical symptoms. The aim of this study is to analyze clinical association of functional polymorphisms in the genes coding for enzymes involved in histamine homeostasis with...

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Share to Aged, 80 and over
Share to Anti-Inflammatory Agents, Non-Steroidal

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 23152756
DOI: 10.1371/journal.pone.0047571
PMCID: PMC3495953

Genes

DAO
HDC
HNMT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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