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Article

The transcription factor EGR1 regulates metastatic potential of v-src transformed sarcoma cells.

Cellular and molecular life sciences : CMLS - 1 Oct 2010

Cermák Vladimír, Kosla Jan, Plachý Jirí, Trejbalová Katerina, Hejnar Jirí, Dvorák Michal

Abstract excerpt

Metastatic spreading of cancer cells is a highly complex process directed primarily by the interplay between tumor microenvironment, cell surface receptors, and actin cytoskeleton dynamics. To advance our understanding of metastatic cancer dissemination, we have developed a model system that is based on two v-src transformed chicken sarcoma cell lines-the highly metastatic parental PR9692 and a non-metastasizing...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 20505979
DOI: 10.1007/s00018-010-0395-6
PMCID: PMC11115510

Genes

EGR1
HAS2
MYL9
MYO10

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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