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Article

Relapse kinetics in acute myeloid leukaemias with MLL translocations or partial tandem duplications within the MLL gene.

British journal of haematology - 1 Jun 2014

Ommen Hans B, Hokland Peter, Haferlach Torsten, Abildgaard Lotte, Alpermann Tamara, Haferlach Claudia, Kern Wolfgang, Schnittger Susanne

Abstract excerpt

Correct action upon re-emergence of minimal residual disease in acute myeloid leukaemia (AML) patients has not yet been established. The applicability of demethylating agents and use of allogeneic stem cell transplantation will be dependent on pre-relapse AML growth rates. We here delineate molecular growth kinetics of AML harbouring MLL partial tandem duplication (MLL-PTD; 37 cases) compared to those harbouring...

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Topics

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Share to Gene Duplication
Share to Genes, Neoplasm

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Histone-Lysine N-Methyltransferase

Share to Myeloid-Lymphoid Leukemia Protein

Share to Neoplasm, Residual

Share to Recurrence

Share to Tandem Repeat Sequences

Share to Translocation, Genetic

Source

Identifiers

PMID: 24611505
DOI: 10.1111/bjh.12792

Genes

FLT3
RUNX1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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