Article

Optimizing the Efficacy of Vaccine-Induced Immunotherapy in Melanomas

2025-01-08

Abstract excerpt

Cancer therapeutic vaccines are used to strengthen a patient’s own immune system by amplifying existing immune responses. Intralesional administration of the bacteria-based emm55 vaccine together with the PD1 checkpoint inhibitor produced a strong anti-tumor effect against the B16 melanoma murine model. However, it is not trivial to design an optimal order and frequency of injections for combination therapies. Her...

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Literature Corpus work: 15b030f7-99e3-5c25-873f-2db517778fae
DOI: 10.1101/2025.01.06.631283

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