Article
Growth differentiation factor 6 as a putative risk factor in neuromuscular degeneration.
PloS one - 1 Jan 2014
DuVal Michèle G, Gilbert Matthew J H, Watson D Ezekiel, Zerulla Tanja C, Tierney Keith B, Allison W Ted
Abstract excerpt
Mutation of Glass bottom boat, the Drosophila homologue of the bone morphogenetic protein or growth/differentiation factor (BMP/GDF) family of genes in vertebrates, has been shown to disrupt development of neuromuscular junctions (NMJ). Here we tested whether this same conclusion can be broadened to vertebrate BMP/GDF genes. This analysis was also extended to consider whether such genes are required for NMJ...
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