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Identification of a dominant epitope in the hemagglutinin of an Asian highly pathogenic avian influenza H5N1 clade 1 virus by selection of escape mutants.

Avian diseases - 1 Mar 2010

Ferreira Helena Lage, Lambrecht Bénédicte, van Borm Steven, Torrieri-Dramard Lea, Klatzmann David, Bellier Bertrand, van den Berg Thierry

Abstract excerpt

H5N1 avian influenza virus has caused widespread infection in poultry and wild birds, and has the potential to emerge as a pandemic threat to humans. The hemagglutinin (HA) is a glycoprotein on the surface of the virus envelope. Understanding its antigenic structure is essential for designing novel vaccines that can inhibit virus infection. The aim of this study was to map the amino acid substitutions that...

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Source

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PMID: 20521695
DOI: 10.1637/8750-033009-ResNote.1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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