Article
Complement factor H gene associations with end-stage kidney disease in African Americans.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association - 1 Jul 2014
Bonomo Jason A, Palmer Nicholette D, Hicks Pamela J, Lea Janice P, Okusa Mark D, Langefeld Carl D, Bowden Donald W, Freedman Barry I
Abstract excerpt
BACKGROUND: Mutations in the complement factor H gene (CFH) region associate with renal-limited mesangial proliferative forms of glomerulonephritis including IgA nephropathy (IgAN), dense deposit disease (DDD) and C3 glomerulonephritis (C3GN). Lack of kidney biopsies could lead to under diagnosis of CFH-associated end-stage kidney disease (ESKD) in African Americans (AAs), with incorrect attribution to other...
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