Article
Differential codon adaptation between dsDNA and ssDNA phages in Escherichia coli.
Molecular biology and evolution - 1 Jun 2014
Chithambaram Shivapriya, Prabhakaran Ramanandan, Xia Xuhua
Abstract excerpt
Because phages use their host translation machinery, their codon usage should evolve toward that of highly expressed host genes. We used two indices to measure codon adaptation of phages to their host, rRSCU (the correlation in relative synonymous codon usage [RSCU] between phages and their host) and Codon Adaptation Index (CAI) computed with highly expressed host genes as the reference set (because phage...
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