Article
Genome landscapes and bacteriophage codon usage.
PLoS computational biology - 29 Feb 2008
Lucks Julius B, Nelson David R, Kudla Grzegorz R, Plotkin Joshua B
Abstract excerpt
Across all kingdoms of biological life, protein-coding genes exhibit unequal usage of synonymous codons. Although alternative theories abound, translational selection has been accepted as an important mechanism that shapes the patterns of codon usage in prokaryotes and simple eukaryotes. Here we analyze patterns of codon usage across 74 diverse bacteriophages that infect E. coli, P. aeruginosa, and L. lactis as...
Topics
- Bacteriophages
- Biological Evolution
- Chromosome Mapping
- Computer Simulation
- Evolution, Molecular
- Genes, Viral
- Genetic Variation
- Genome, Viral
- Models, Genetic
- Species Specificity
