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Article

Genome-Wide Association Studies and Meta-Analyses for Congenital Heart Defects.

Circulation. Cardiovascular genetics - 1 Jun 2017

Agopian A J, Goldmuntz Elizabeth, Hakonarson Hakon, Sewda Anshuman, Taylor Deanne, Mitchell Laura E

Abstract excerpt

BACKGROUND: Maternal and inherited (ie, case) genetic factors likely contribute to the pathogenesis of congenital heart defects, but it is unclear whether individual common variants confer a large risk. METHODS AND RESULTS: To evaluate the relationship between individual common maternal/inherited genotypes and risk for heart defects, we conducted genome-wide association studies in 5 cohorts. Three cohorts were...

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Identifiers

PMID: 28468790
DOI: 10.1161/CIRCGENETICS.116.001449
PMCID: PMC5539991

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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