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Article

Connexin 30 sets synaptic strength by controlling astroglial synapse invasion.

Nature neuroscience - 1 Apr 2014

Pannasch Ulrike, Freche Dominik, Dallérac Glenn, Ghézali Grégory, Escartin Carole, Ezan Pascal, Cohen-Salmon Martine, Benchenane Karim, Abudara Veronica, Dufour Amandine, Lübke Joachim H R, Déglon Nicole, Knott Graham, Holcman David, Rouach Nathalie

Abstract excerpt

Astrocytes play active roles in brain physiology by dynamic interactions with neurons. Connexin 30, one of the two main astroglial gap-junction subunits, is thought to be involved in behavioral and basic cognitive processes. However, the underlying cellular and molecular mechanisms are unknown. We show here in mice that connexin 30 controls hippocampal excitatory synaptic transmission through modulation of...

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Identifiers

PMID: 24584052
DOI: 10.1038/nn.3662

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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