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Connexin26 expression in brain parenchymal cells demonstrated by targeted connexin ablation in transgenic mice

30 Jun 2011

Abstract excerpt

Astrocytes are known to express the gap junction forming proteins connexin30 (Cx30) and connexin43 (Cx43), but it has remained controversial whether these cells also express connexin26 (Cx26). To investigate this issue further, we examined immunofluorescence labelling of glial connexins in wild-type vs. transgenic mice with targeted deletion of Cx26 in neuronal and glial cells (Cx26fl/fl:Nestin-Cre mice). The...

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PMID: 21714813
DOI: 10.1111/j.1460-9568.2011.07741.x

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