Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Altered miRNA expression in canine retinas during normal development and in models of retinal degeneration.

BMC genomics - 1 Mar 2014

Genini Sem, Guziewicz Karina E, Beltran William A, Aguirre Gustavo D

Abstract excerpt

BACKGROUND: Although more than 246 loci/genes are associated with inherited retinal diseases, the mechanistic events that link genetic mutations to photoreceptor cell death are poorly understood. miRNAs play a relevant role during retinal development and disease. Thus, as a first step in characterizing miRNA involvement during disease expression and progression, we examined miRNAs expression changes in normal...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Age Factors
Share to Cluster Analysis
Share to Disease Progression

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Dog Diseases

Share to MicroRNAs

Share to Retina

Share to Retinal Degeneration

Source

Open in PubMed Open full text

Identifiers

PMID: 24581223
DOI: 10.1186/1471-2164-15-172
PMCID: PMC4029133

Genes

PRCD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Altered miRNA expression in canine retinas during normal development and in models of retinal degeneration.PMID 24581223Read ↗

FAM161A and TTC8 are Differentially Expressed in Non-Allelelic Early Onset Retinal Degeneration.Semantic proximity Read ↗

Up-Regulation of Tumor Necrosis Factor Superfamily Genes in Early Phases of Photoreceptor DegenerationSemantic proximity Read ↗

Involvement of Innate Immune System in Late Stages of Inherited Photoreceptor Degeneration.Semantic proximity Read ↗

Expression Profiling Analysis Reveals Key MicroRNA–mRNA Interactions in Early Retinal Degeneration in Retinitis PigmentosaSemantic proximity Read ↗

The use of canine models of inherited retinal degeneration to test novel therapeutic approaches.Semantic proximity Read ↗

Age-dependent disease expression determines remodeling of the retinal mosaic in carriers of RPGR exon ORF15 mutations.Semantic proximity Read ↗

PRCD-associated retinitis pigmentosa in dogs and humans.Semantic proximity Read ↗

Identification of Gene Expression Changes Associated with the Progression of Retinal Degeneration in therd1MouseSemantic proximity Read ↗

Strong upregulation of inflammatory genes accompanies photoreceptor demise in canine models of retinal degenerationSemantic proximity Read ↗

Increased expression of MERTK is associated with a unique form of canine retinopathy.Semantic proximity Read ↗

Genome-wide association study in RPGRIP1(-/-) dogs identifies a modifier locus that determines the onset of retinal degeneration.Semantic proximity Read ↗

Molecular aspects of retinal degenerative diseases.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.