Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Age-dependent disease expression determines remodeling of the retinal mosaic in carriers of RPGR exon ORF15 mutations.

Investigative ophthalmology & visual science - 1 Aug 2009

Beltran William A, Acland Gregory M, Aguirre Gustavo D

Abstract excerpt

PURPOSE: To characterize the retinal histopathology in carriers of X-linked progressive retinal atrophy (XLPRA1 and XLPRA2), two canine models of X-linked retinitis pigmentosa caused, respectively, by a stop and a frameshift mutation in RPGRORF15. METHODS: Retinas of XLPRA2 and XLPRA1 carriers of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Dog Diseases
Share to Fluorescent Antibody Technique, Indirect
Share to Genetic Diseases, X-Linked

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Guanine Nucleotide Exchange Factors

Share to In Situ Nick-End Labeling

Share to Open Reading Frames

Share to Photoreceptor Cells, Vertebrate

Share to Retinitis Pigmentosa

Source

Open in PubMed Open full text

Identifiers

PMID: 19255154
DOI: 10.1167/iovs.08-3364
PMCID: PMC2718058

Genes

RPGR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19255154-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Age-dependent disease expression determines remodeling of the retinal mosaic in carriers of RPGR exon ORF15 mutations.PMID 19255154Read ↗

Variegated yet non-random rod and cone photoreceptor disease patterns in RPGR-ORF15-associated retinal degeneration.Semantic proximity Read ↗

RPGR-associated retinal degeneration in human X-linked RP and a murine model.Semantic proximity Read ↗

Altered miRNA expression in canine retinas during normal development and in models of retinal degeneration.Semantic proximity Read ↗

Molecular studies of phenotype variation in canine RPGR-XLPRA1.Semantic proximity Read ↗

Retinal histopathology of an XLRP carrier with a mutation in the RPGR exon ORF15.Semantic proximity Read ↗

Successful arrest of photoreceptor and vision loss expands the therapeutic window of retinal gene therapy to later stages of diseaseSemantic proximity Read ↗

Histopathologic study of X-linked cone-rod dystrophy (CORDX1) caused by a mutation in the RPGR exon ORF15.Semantic proximity Read ↗

Rd9 is a naturally occurring mouse model of a common form of retinitis pigmentosa caused by mutations in RPGR-ORF15.Semantic proximity Read ↗

Up-Regulation of Tumor Necrosis Factor Superfamily Genes in Early Phases of Photoreceptor DegenerationSemantic proximity Read ↗

Intravitreal injection of ciliary neurotrophic factor (CNTF) causes peripheral remodeling and does not prevent photoreceptor loss in canine RPGR mutant retina.Semantic proximity Read ↗

RPGR-Associated Dystrophies: Clinical, Genetic, and Histopathological Features.Semantic proximity Read ↗

FAM161A and TTC8 are Differentially Expressed in Non-Allelelic Early Onset Retinal Degeneration.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.