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Article

FAM161A and TTC8 are Differentially Expressed in Non-Allelelic Early Onset Retinal Degeneration.

Advances in experimental medicine and biology - 1 Jan 2016

Downs Louise M, Aguirre Gustavo D

Abstract excerpt

Ciliary genes FAM161A and TTC8 have been implicated in retinal degeneration (RD) in humans and in dogs. The identification of FAM161A and TTC8 mutations in canine RD is exciting as there is the potential to develop novel large animal models for RD. However, the disease phenotypes in the dog and the roles of abnormal genes in disease pathology have yet to be fully characterized. The present study evaluated the...

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Identifiers

PMID: 26427412
DOI: 10.1007/978-3-319-17121-0_27
PMCID: PMC4602411

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