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Article

Epigenetic alterations in sporadic basal cell carcinomas.

Archives of dermatological research - 1 Aug 2014

Stamatelli Angeliki, Vlachou Christina, Aroni Kiriaki, Papassideri Issidora, Patsouris Efstratios, Saetta Angelica A

Abstract excerpt

Basal cell carcinoma (BCC) is the most common malignant human neoplasm characterized by slow growth and virtual absence of metastases. Recently, it has become evident that along with genetic mutations epigenetic alterations play a key role in the pathogenesis of human cancer. We searched for promoter methylation of hMLH1, RASSF1A, DAPK, APC, DCR1 and DCR2 genes and BRAF mutations in BCCs in association with the...

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Source

Identifiers

PMID: 24573469
DOI: 10.1007/s00403-014-1454-x

Genes

APC
BRAF
RASSF1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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