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Article

Different methylation and microRNA expression pattern in male and female familial breast cancer.

Journal of cellular physiology - 1 Jun 2013

Pinto Rosamaria, Pilato Brunella, Ottini Laura, Lambo Rossana, Simone Giovanni, Paradiso Angelo, Tommasi Stefania

Abstract excerpt

Epigenetic regulation, has been very scarcely explored in familial breast cancer (BC). In the present study RASSF1A and RAR beta promoter methylation and miR17, miR21, miR 124, and let-7a expression were investigated to highlight possible differences of epigenetic regulation between male and female familial BC, also in comparison with sporadic BC. These epigenetic alterations were studied in 56 familial BC...

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Share to BRCA1 Protein
Share to Breast Neoplasms, Male

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Receptors, Retinoic Acid

Share to Tumor Suppressor Proteins

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Identifiers

PMID: 23160909
DOI: 10.1002/jcp.24281

Genes

BRCA1

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