Article
Overexpression of genes involved in miRNA biogenesis in medullary thyroid carcinomas with RET mutation.
Endocrine - 1 Nov 2014
Puppin Cinzia, Durante Cosimo, Sponziello Marialuisa, Verrienti Antonella, Pecce Valeria, Lavarone Elisa, Baldan Federica, Campese Antonio Francesco, Boichard Amelie, Lacroix Ludovic, Russo Diego, Filetti Sebastiano, Damante Giuseppe
Abstract excerpt
Abnormal expression of non-coding micro RNA (miRNA) has been described in medullary thyroid carcinoma (MTC). Expression of genes encoding factors involved in miRNA biogenesis results often deregulated in human cancer and correlates with aggressive clinical behavior. In this study, expression of four genes involved in miRNA biogenesis (DICER, DROSHA, DCGR8, and XPO5) was investigated in 54 specimens of MTC. Among...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
