Article
Unraveling the Significance of DGCR8 and miRNAs in Thyroid Carcinoma.
Cells - 22 Mar 2024
Rodrigues Lia, Da Cruz Paula Arnaud, Soares Paula, Vinagre João
Abstract excerpt
MicroRNAs (miRNAs) act as negative regulators for protein-coding gene expression impacting cell proliferation, differentiation, and survival. These miRNAs are frequently dysregulated in cancer and constitute classes of blood-based biomarkers useful for cancer detection and prognosis definition. In thyroid cancer (TC), the miRNA biogenesis pathway plays a pivotal role in thyroid gland formation, ensuring proper...
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