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Article

Arp5 is a key regulator of myocardin in smooth muscle cells.

The Journal of cell biology - 3 Mar 2014

Morita Tsuyoshi, Hayashi Ken'ichiro

Abstract excerpt

Myocardin (Myocd) and Myocd-related transcription factors (MRTFs) are robust coactivators of serum response factor (SRF). RPEL motifs are monomeric globular actin (G-actin) binding elements that regulate MRTF localization and activity. However, the function of the RPEL motif in Myocd is largely unknown because of its low affinity for G-actin. Here, we demonstrated that the Myocd RPEL motif bound to actin-related...

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Source

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Identifiers

PMID: 24567363
DOI: 10.1083/jcb.201307158
PMCID: PMC3941051

Genes

SRF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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