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Article

In vivo effect of a TLR5 SNP (C1205T) on Salmonella enterica serovar Typhimurium infection in weaned, specific pathogen-free Landrace piglets.

Microbiology and immunology - 1 Jun 2018

Muneta Yoshihiro, Arai Nobuo, Yakabe Yoko, Eguchi Masahiro, Shibahara Tomoyuki, Sakuma Akiko, Shinkai Hiroki, Uenishi Hirohide, Hirose Kensuke, Akiba Masato

Abstract excerpt

Toll-like receptor 5 is a pattern-recognition receptor for bacterial flagellin. We previously reported that a single nucleotide polymorphism (SNP) of swine TLR5, C1205T, impairs recognition of Salmonella typhimurium (ST) flagellin and ethanol-killed Salmonella Choleraesuis (SC). In the present study, weaned, specific pathogen-free (SPF) Landrace piglets with CC, CT or TT genotypes were orally infected with ST...

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Identifiers

PMID: 29660148
DOI: 10.1111/1348-0421.12591

Genes

TLR5

Variants

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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