Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Survivin mRNA expression in blood as a predictor of the response to EGFR-tyrosine kinase inhibitors and prognosis in patients with non-small cell lung cancer.

Medical oncology (Northwood, London, England) - 1 Apr 2014

Shi Wei-Lin, Li Jian, Bao Quan-Lei, Wu Jian-Nong, Ge Li-Ping, Zhu Li-Rong, Wang Yi, Zhu Wen-Fang

Abstract excerpt

The epidermal growth factor receptor (EGFR) mutations have been proven to be a reliable predictive marker for the response to EGFR-tyrosine kinase inhibitors (TKIs) in patients with non-small cell lung cancer (NSCLC). However, the responses to EGFR-TKIs vary even among patients with EGFR mutation. Recent study showed that survivin overexpression attenuated EGFR-TKI-induced apoptosis and inhibited the antitumor...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Carcinoma, Non-Small-Cell Lung
Share to Inhibitor of Apoptosis Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Predictive Value of Tests

Share to Proportional Hazards Models

Share to Protein-Tyrosine Kinases

Share to Real-Time Polymerase Chain Reaction

Share to ROC Curve

Share to Survivin

Source

Identifiers

PMID: 24563335
DOI: 10.1007/s12032-014-0893-8

Genes

EGFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Survivin mRNA expression in blood as a predictor of the response to EGFR-tyrosine kinase inhibitors and prognosis in patients with non-small cell lung cancer.PMID 24563335Read ↗

Prognostic significance of survivin polymorphisms on non-small cell lung cancer survival.Semantic proximity Read ↗

Association between survivin genetic polymorphisms and epidermal growth factor receptor mutation in non-small-cell lung cancer.Semantic proximity Read ↗

Survivin and Tumorigenesis: Molecular Mechanisms and Therapeutic StrategiesSemantic proximity Read ↗

Investigations of survivin: the past, present and futureSemantic proximity Read ↗

The role of survivin as a new target of diagnosis and treatment in human cancer.Semantic proximity Read ↗

Recent Advances on Small-Molecule Survivin InhibitorsSemantic proximity Read ↗

Role of survivin in EGFR inhibitor-induced apoptosis in non-small cell lung cancers positive for EGFR mutations.Semantic proximity Read ↗

Nuclear survivin as a biomarker for non-small-cell lung cancerSemantic proximity Read ↗

Survivin Small Molecules Inhibitors: Recent Advances and ChallengesSemantic proximity Read ↗

Survivin: A molecular biomarker in cancer.Semantic proximity Read ↗

The clinical significance of splice variants and subcellular localisation of survivin in non-small cell lung cancersSemantic proximity Read ↗

Survivin as a Therapeutic Target for the Treatment of Human CancerSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.