Article
Association between survivin genetic polymorphisms and epidermal growth factor receptor mutation in non-small-cell lung cancer.
International journal of medical sciences - 1 Jan 2016
Liu Tu-Chen, Hsieh Ming-Ju, Wu Wen-Jun, Chou Ying-Erh, Chiang Whei-Ling, Yang Shun-Fa, Su Shih-Chi, Tsao Thomas Chang-Yao
Abstract excerpt
Survivin is an anti-apoptotic protein that is implicated in the regulation of apoptosis and cell cycle in various types of cancers. The current study explored the effect of survivin gene polymorphisms and EGFR mutations in non-small-cell lung carcinoma (NSCLC) patients. A total of 360 participants, including 291 adenocarcinoma lung cancer and 69 squamous cell carcinoma lung cancer patients, were selected for the...
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