Article
Multiple nuclear localization signals mediate nuclear localization of the GATA transcription factor AreA.
Eukaryotic cell - 1 Apr 2014
Hunter Cameron C, Siebert Kendra S, Downes Damien J, Wong Koon Ho, Kreutzberger Sara D, Fraser James A, Clarke David F, Hynes Michael J, Davis Meryl A, Todd Richard B
Abstract excerpt
The Aspergillus nidulans GATA transcription factor AreA activates transcription of nitrogen metabolic genes in response to nitrogen limitation and is known to accumulate in the nucleus during nitrogen starvation. Sequence analysis of AreA revealed multiple nuclear localization signals (NLSs), five putative classical NLSs conserved in fungal AreA orthologs but not in the Saccharomyces cerevisiae functional...
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