Article
Genetic and molecular characterization of murine GATA-1 in Aspergillus defines a critical role for the N-terminal finger.
Genes and function - 1 Feb 1997
Caddick M X, Peters D G, Hooley P, Nayler A
Abstract excerpt
We have utilized Aspergillus nidulans as a model system for the characterization of the major vertebrate transcription factor GATA-1. This has been achieved both by analysing the function of murine GATA-1 directly and by using direct gene replacement to introduce chimaeric areA::GATA-1 derivatives at the areA locus, which encodes a GATA factor involved in regulating nitrogen metabolism in A. nidulans. Although...
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