Article
Functional analysis of TamA, a coactivator of nitrogen-regulated gene expression in Aspergillus nidulans.
Molecular genetics and genomics : MGG - 1 Jun 2001
Small A J, Todd R B, Zanker M C, Delimitrou S, Hynes M J, Davis M A
Abstract excerpt
The tam A gene of Aspergillus nidulans encodes a 739-amino acid protein with similarity to Uga35p/Dal81p/DurLp of Saccharomyces cerevisiae. It has been proposed that TamA functions as a co-activator of AreA, the major nitrogen regulatory protein in A. nidulans. Because AreA functions as a transcriptional activator under nitrogen-limiting conditions, we investigated whether TamA was also present in the nucleus. We...
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