Article
The relationship between DNA methylation, genetic and expression inter-individual variation in untransformed human fibroblasts.
Genome biology - 20 Feb 2014
Wagner James R, Busche Stephan, Ge Bing, Kwan Tony, Pastinen Tomi, Blanchette Mathieu
Abstract excerpt
BACKGROUND: DNA methylation plays an essential role in the regulation of gene expression. While its presence near the transcription start site of a gene has been associated with reduced expression, the variation in methylation levels across individuals, its environmental or genetic causes, and its association with gene expression remain poorly understood. RESULTS: We report the joint analysis of sequence...
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