CYP1A2 polymorphism -1545C > T (rs2470890) is associated with increased side effects to clozapine.

doi:10.1186/1471-244X-14-50

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Article

CYP1A2 polymorphism -1545C > T (rs2470890) is associated with increased side effects to clozapine.

BMC psychiatry - 20 Feb 2014

Viikki Merja, Kampman Olli, Seppälä Niko, Mononen Nina, Lehtimäki Terho, Leinonen Esa

Abstract excerpt

BACKGROUND: Cytochrome P450 1A2 gene (CYP1A2) polymorphisms have been suggested to be associated with increased side effects to antipsychotics. However, studies on this are scarce and have been conducted with either various antipsychotics or only in small samples of patients receiving clozapine. The aim of the present study was to test for an association between the CYP1A2 -1545C > T (rs2470890) polymorphism and...

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Identifiers

PMID: 24555493
DOI: 10.1186/1471-244X-14-50
PMCID: PMC3937243

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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