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Article

Interaction of the HOPS complex with Syntaxin 17 mediates autophagosome clearance in Drosophila.

Molecular biology of the cell - 1 Apr 2014

Takáts Szabolcs, Pircs Karolina, Nagy Péter, Varga Ágnes, Kárpáti Manuéla, Hegedűs Krisztina, Kramer Helmut, Kovács Attila L, Sass Miklós, Juhász Gábor

Abstract excerpt

Homotypic fusion and vacuole protein sorting (HOPS) is a tethering complex required for trafficking to the vacuole/lysosome in yeast. Specific interaction of HOPS with certain SNARE (soluble NSF attachment protein receptor) proteins ensures the fusion of appropriate vesicles. HOPS function is less well characterized in metazoans. We show that all six HOPS subunits (Vps11 [vacuolar protein sorting 11]/CG32350,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 24554766
DOI: 10.1091/mbc.E13-08-0449
PMCID: PMC3982998

Genes

NSF
UVRAG

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Interaction of the HOPS complex with Syntaxin 17 mediates autophagosome clearance in Drosophila.PMID 24554766Read ↗

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