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Article

Mutation of SLC35D3 causes metabolic syndrome by impairing dopamine signaling in striatal D1 neurons.

PLoS genetics - 1 Feb 2014

Zhang Zhe, Hao Chan-Juan, Li Chang-Gui, Zang Dong-Jie, Zhao Jing, Li Xiao-Nan, Wei Ai-Hua, Wei Zong-Bo, Yang Lin, He Xin, Zhen Xue-Chu, Gao Xiang, Speakman John R, Li Wei

Abstract excerpt

Obesity is one of the largest health problems facing the world today. Although twin and family studies suggest about two-thirds of obesity is caused by genetic factors, only a small fraction of this variance has been unraveled. There are still large numbers of genes to be identified that cause variations in body fatness and the associated diseases encompassed in the metabolic syndrome (MetS). A locus near a...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 24550737
DOI: 10.1371/journal.pgen.1004124
PMCID: PMC3923682

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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