Chromosome 3p loss of heterozygosity is associated with a unique metabolic network in clear cell renal carcinoma.

Abstract excerpt

Several common oncogenic pathways have been implicated in the emergence of renowned metabolic features in cancer, which in turn are deemed essential for cancer proliferation and survival. However, the extent to which different cancers coordinate their metabolism to meet these requirements is largely unexplored. Here we show that even in the heterogeneity of metabolic regulation a distinct signature encompassed...

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