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A proteogenomic analysis of clear cell renal cell carcinoma in a Chinese population

19 Apr 2022

Abstract excerpt

Clear cell renal cell carcinoma (ccRCC) is a common and aggressive subtype of renal cancer. Here we conduct a comprehensive proteogenomic analysis of 232 tumor and adjacent non-tumor tissue pairs from Chinese ccRCC patients. By comparing with tumor adjacent tissues, we find that ccRCC shows extensive metabolic dysregulation and an enhanced immune response. Molecular subtyping classifies ccRCC tumors into three...

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PMID: 35440542
DOI: 10.1038/s41467-022-29577-x

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