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Article

Effects of the HIF-1α and NF-κB loop on epithelial-mesenchymal transition and chemoresistance induced by hypoxia in pancreatic cancer cells.

Oncology reports - 1 Apr 2014

Cheng Zhuo-Xin, Wang Da-Wei, Liu Tao, Liu Wei-Xin, Xia Wei-Bin, Xu Jian, Zhang Ying-Hai, Qu Yi-Kun, Guo Lin-Qi, Ding Long, Hou Jie, Zhong Zhao-Hua

Abstract excerpt

Hypoxia is a microenvironmental factor which plays a critical role in tumor development and chemoresistance. Epithelial-to-mesenchymal transition (EMT) induced by hypoxia is one of the critical causes of treatment failure and chemoresistance in different types of human cancers. Stabilization of t...

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Source

Identifiers

PMID: 24535079
DOI: 10.3892/or.2014.3022

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24535079-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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