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Article

Stationary phase-specific virulence factor overproduction by a lasR mutant of Pseudomonas aeruginosa.

PloS one - 1 Jan 2014

Cabeen Matthew T

Abstract excerpt

Secreted virulence factors of the human pathogen Pseudomonas aeruginosa are often under quorum sensing control. Cells lacking the quorum-sensing regulator LasR show reduced virulence factor production under typical laboratory conditions and are hypo-virulent in short-term animal infection models, yet lasR mutants are frequently associated with long-term infection in cystic fibrosis patients. Here, I show that in...

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Identifiers

PMID: 24533146
DOI: 10.1371/journal.pone.0088743
PMCID: PMC3923063

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