Article
The mechanism of nucleic acid melting by a CspA family protein.
Journal of molecular biology - 12 Mar 2004
Phadtare Sangita, Inouye Masayori, Severinov Konstantin
Abstract excerpt
Cold-shock proteins of the CspA family help bacterial cells to acclimate to low temperatures. Some Csps bind single-stranded nucleic acids and destabilize nucleic acid secondary structures in vitro, and act as transcription antiterminators in vivo and in vitro. Nucleic acid melting by Escherichia coli CspE is critical for its ability to support low-temperature survival of the cell. Here, we explore the molecular...
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