Article
CXCR3 polymorphism is associated with male gender and pleuritis in patients with systemic lupus erythematosus.
Human immunology - 1 May 2014
Im Churl Hyun, Park Ji Ah, Kim Jeong Yeon, Lee Eun Young, Lee Eun Bong, Kim Yeonjung, Song Yeong Wook
Abstract excerpt
BACKGROUND: Systemic lupus erythematosus (SLE) is a chronic inflammatory autoimmune disease involving multiple organs. Chemokines and their receptors play an important role in the pathogenesis of SLE. Lymphocytes expressing CXCR3, chemokine receptors of CXCL4, 9, 10, and 11, increase in patients...
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