Article
Association of chemokine CXCL12-3'G801A polymorphism with systemic lupus erythematosus in a Han Chinese population.
Lupus - 1 May 2012
Wu F-X, Luo X-Y, Wu L-J, Yang M-H, Long L, Liu N-T, Zhou B, Zeng X-F, Yang C-de, Yuan G-H
Abstract excerpt
CXCL12, also known as stromal cell-derived factor (SDF-1), is a CXC chemokine. Recent reports have shown that CXCL12 might play key roles in a murine model of lupus and in patients with systemic lupus erythematosus (SLE). A common variant at position 801 in 3'-untranslated region in CXCL12 gene (designated CXCL12-3'G801A) has been reported in association with autoimmune diseases, such as type 1 diabetes and...
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