Article
Targetome profiling and functional genetics implicate miR-618 in lymphomagenesis.
Epigenetics - 1 May 2014
Fu Alan, Hoffman Aaron E, Liu Ran, Jacobs Daniel I, Zheng Tongzhang, Zhu Yong
Abstract excerpt
Despite the voluminous body of observational evidence concerning the role of miRNAs in cancer, significant knowledge gaps remain concerning the molecular circumstances that underlie the miRNA-cancer connection. In this study, we employ a multidisciplinary approach to establish an association between miR-618 and non-Hodgkin lymphoma (NHL) in a human population and attempt to explicate this association at the...
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